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What Is KirklandHormone Replacement Therapy?
HRT (also known as hormone therapy, menopausal hormone therapy, and estrogen replacement therapy) uses female hormones — estrogen and progesterone — to treat common symptoms of menopause and aging. Doctors can prescribe it during or after menopause.
After your period stops, your hormone levels fall, causing uncomfortable symptoms like hot flashes and vaginal dryness, and sometimes conditions like osteoporosis. Kirkland HRT replaces hormones your body no longer makes. It’s the most effective treatment for menopause symptoms.
Natural Hormonal Replacement Therapy
The economics of bioidentical hormones
Why doesn't modern medicine use bioidentical hormones (hormones identical to what our body makes) to "replace" what is missing? It's sad to say, but the main reason is that there is no money in it.
Pharmaceutical companies can only patent what they invent in a laboratory. They are not able to patent what Nature makes. And its only through holding a patent on a drug that they can mark up the price enough to make a good profit.
(The mark up on drugs like Premarin and Prempro is very high, with mark up on many drugs upwards of 10,000%. Premarin is available in Europe for $8.95/100, in Canada for $22.46/100 in the United States for $55.42. Price variations for Prempro are $5.75/28 in Europe, $14.33/28 in Canada and $31.09/28 in the United States). These price variations begin to reveal the profit margins pharmaceutical companies have with these drugs. They are really a cash cow for these companies.
A point of confusion for some people is the difference between side effects and risks when taking a prescriptive drug. This is certainly true when it comes to hormone replacement therapy or HRT. HRT refers to synthetic hormones prescribed primarily to relieve menopause related complaints such as hot flashes, night sweats, erratic periods, excessive bleeding during perimenopause, etc.
Risks associated with HRT
There are long term risks associated with taking prescriptive hormones as part of replacement therapy. You may have taken prescriptive hormones for years with no side effects whatsoever, and they may have dramatically relieved your menopausal hot flashes, sweats and other complaints. Yet you are now at greater risk for a variety of serious illnesses including breast cancer, uterine cancer, stroke and heart attack to name a few. These are the risks associated with HRT. Research studies have found so many serious risks associated with hormone replacement therapy that most medical doctors are unwilling to routinely prescribe hormone replacement for relief of menopause related complaints. Rightly so, they don't want to put their patient's at risk for life threatening conditions.
Let's look more closely at the risks associated with replacement therapy. Much of our knowledge of these risks comes from the Women's Health Initiative, a study that tracked the health of thousands of women, some taking hrt and others not. The study was eventually stopped as it became clear that there was a dramatically increased risk of breast cancer among the women undergoing HRT. Because of the complex nature of the study, the results are difficult to summarize succinctly. Numerous other studies have also clarified the risks and benefits associated with hormone replacement. Here is a broad picture of the level of risk associated with hormone replacement, followed by the benefits.
Hormone replacement therapy risks
- Breast cancer risk increased by 24 percent with combined estrogen / progestin HRT
- Risk of ischemic stroke increased by 41 percent with medium to high dose HRT, but much less risk with ultra low dose hormone replacement
- Heart attack risk increases by 29 percent for those taking HRT
- Slightly increased risk of ovarian cancer when only estrogen is taken for more than 10 years
- Twenty-one percent increased risk of kidney stones
- Higher risk of developing gall stones
Hormone replacement benefits
- Relief of menopause related complaints
- Increases bone density
- Reduces risk for colon-rectal cancer
- Decreases risk of macular (eye) degeneration and loss of vision associated with aging
The side effects of HRT
Side effects are generally considered to be any temporary complaints that are experienced while taking a drug. Side effects often resolve soon after stopping the medication. Using this description, the side effects of hormone replacement are not well known. These side effects vary depending on which combination of hormones one is taking and the specific synthetic forms used. Some of the more common side effects of prescriptive forms of estrogen, progesterone and combinations of both are as follows.
- Breast pain, enlargement and tenderness is associated with the stimulatory effect of estrogen
- Nausea and vomiting with the use of estrogen HRT taken by mouth
- Vaginal bleeding can occur in association with oral estrogen
- Darkened skin spots tend to occur on the face
- Headaches of a migraine type are associated with taking synthetic progesterone or progestins
- Depression is a common complaint that is found to be a result of taking progestins
- Greasy skin and acne are also associated with progestin use
Women are wisely looking for alternatives to hormone replacement. Fearing the risks associated with it, added to the side effects of prescriptive hormones, they are not too excited by it. Researchers and academics argue for and against hormone replacement.
The author's of a 2008 study titled the Women's International Study of Long-Duration Oestrogen after the Menopausesuggested that their study demonstrated such significant benefits for relief of menopause complaints that HRTshould be reconsidered by many women.
One of their colleagues (not an author of the study) reviewed the results of their study and came up with the opposite conclusion. Underscoring her concerns regarding the risks of hormone replacement therapy, Professor Anne Kavanagh of the University of Melbourne recently countered their claims as to the benefits of hormone replacement therapy. Professor Kavanagh points out that the study did not show and overall improvement in the "quality of life" for women in the study.
The existing methods of delivery currently include injection, pills, patches, or gel.
Of the injection method, normally it is done either weekly or fortnightly - but the concern is that there will be peaks and troughs of testosterone levels between the last and next injection. These rises and falls of testosterone level can mean high energy and motivation immediately following the injection, gradually waning to lethargy and perhaps even depression leading up to the next injection.
The pills method also has its problems, because the digestive process. Taking pills causes a mass flood of testosterone to be sent to the liver, which is not about it and metabolizes it into estrogen which defeats the whole purpose. The bottom-line is that you are swallowing a lot more testosterone than ever enters your bloodstream.
Patches do provide a regular supply of testosterone directly into your bloodstream via the skin, the only real down-side with them is skin irritation caused by the patches. Rotating to new sites every day can reduce this.
If you truly must have replacement therapy, then without doubt gel is the best of all options. If provides a steady release every day of the hormone into your blood through the skin, and it has no skin irritation side effects.
Better still would be to consider boosting your own production of testosterone using dietary supplements.
Natural Hormone Replacement Therapy - Does it Really Work?
With publicity about the dangers of hormone replacement therapy (HRT) getting so much publicity, a lot of women are turning to herbs and supplements for hot flashes and other symptoms associated with menopause. Soy, black cohosh, Dong Quai root, and Evening primrose oil have all been promoted for hot flashes and other menopausal symptoms. But do they really work? An initial study of 104 postmenopausal women randomized to 40 g daily of soy or a placebo showed a statistically significant reduction in number of hot flashes that was greater for soy (45%) that was greater than the reduction obtained with placebo (30%). Another study of 351 women age 45-55 with two or more hot flash symptoms per day were randomly assigned to black cohosh, multibotanicals, multibotanicals plus dietary soy counseling, placebo or hormone therapy for one year. Only hormone therapy was associated with significant reductions in hot flashes. Taking dietary soy actually turned out to be less effective at stopping hot flashes than taking a placebo for one year.
Every individual wishes to maintain a youthful appearance. There are several beauty enhancement products available in the market. However, cosmetic products do not provide permanent positive results. They can cause certain complications with the presence of harmful chemicals. As people get older, they lose their charm and youthful appearance. According to the medical survey, this occurs due to the decrease in the hormones in the human body. The natural production gets affected or stopped with aging. The imbalance starts to take place as soon as the individual crosses 20. These changes are experienced by both men and women. There are many reliable clinics in Ohio that offer hormone replacement treatment. It has benefited many individuals in this region.
Hormones are considered to be crucial for the smooth development of the body. They are termed as chemical messengers that flow in the blood systems to promote proper functioning of the mental and physical aspect of human being. There is no denying that with aging, the deficiency starts to occur and thus appropriate measures have to be taken. The reliable clinics have state of the art facilities to offer appropriate solutions to the patients. You can contact experienced and qualified physicians to get detailed information about the entire procedure. Bio-identical hormone replacement therapy is perfectly suited for both men and women. It has proven its worth as an effective medical solution to promote wellness, healthy aging and vitality among the human being.
Fight Depression With Hormone Replacement Therapy
Hot flashes or flushes are described as a sudden feeling of warmth or heat within the body and often with associated sweating. A hot flash can be an intense feeling of heat usually in the upper half of the body but can be experienced in the lower half as well.
The exact cause of hot flashes isn't known but they do know that factors affecting the regulatory area of the brain, the hypothalamus, regulates body temperature. When the brain senses an increase in body temperature it will release chemicals which cause the blood vessels in the skin to dilate in an attempt to release the heat. It is said that estrogen and testosterone allow the body to tolerate changes in core body temperature, therefore, as these hormones decrease in peri-menopause and menopause so does your body's ability to tolerate increased heat.
In my opinion this is only part of the problem. I believe it is more of an imbalance in the hormone family than just a decrease in estrogen and testosterone. In some women, when estrogen is balanced with progesterone, hot flashes decrease or stop altogether. Knowing what is out of balance will help you determine why you have hot flashes in the first place. Hot flashes are not normal, they are one of your body's very intelligent ways of communicating a larger problem.
Lifestyle, stress and dietary habits play a huge role in the occurrence and frequency of hot flashes and night sweats. Known hot flash triggers are:
Physical, Emotional & Dietary Stress
Over the Counter Medications
Know what your triggers are and attempt to avoid them as much as possible. Avoid closed, hot rooms and lower the temperature in your surroundings. Dress in layers and do not wear synthetic clothing as they trap the sweat. Cotton clothing allows your skin to breath. Increase your exercise routine to 30 minutes per day and get sound, quality sleep. Decreasing stress is a no-brainer but not so easy to do. Practice stress reducing techniques and mindfulness. Absolutely avoid processed foods including; boxed and canned goods, fast foods, enriched breads, sugars, sodas, etc. These non-foods put undue stress on your digestive system and ultimately your endocrine system (hormones).
So what's the problem with (HRT) Hormone Replacement Therapy? Most of us have heard the stories, read the articles and have seen the warnings. The possible side-effects of HRT are just a bit too scary for me. Breast and/or uterine cancer, heart disease, blood clots, and stroke being the most prominent. Unfortunately, some of you have even experienced one of these yourself. And, watch out ladies, bio-identical hormone replacement therapy can be dangerous as well. Natural progesterone cream is sold over the counter and being used without knowing one's hormone levels. Hormone creams and gels must be used very carefully and monitored closely with appropriate testing. One of the many problems with using the transdermal creams and gels is that they are absorbed into the subcutaneous fat tissue where they build up and can eventually saturate the tissue and over time start to spill back into the system creating an overdose of the 'free fraction' of the hormone in the body. At this point your cells will down-regulate (not accept) the hormone and you will once again have the symptoms of deficiency while you actually have too much of the hormone in your system. Routine (serum bound) blood tests cannot accurately monitor the use of transdermal creams and gels. Testing must be performed in the free state, otherwise a person will be profoundly overdosed with 'free' hormone levels by the time the blood tests detect any significant changes. I have witnessed many a website advising the use of creams and gels without regard to the individual's symptoms, history or tested levels. This is totally irresponsible and a major problem for women looking for an end to the sometimes debilitating symptoms of menopause. When administering a hormone in a 'free' form you must test for and monitor the hormone in a 'free' form (saliva or serum free). Since hormones are interactive, the problem doesn't end here. Depending on the hormone being overdosed, multiple other imbalances will stream into the system. Hormones given in amounts that exceed normal physiologic needs will cause receptor cell down-regulation (the cells will not accept the hormone once the liver can no longer clear the excessive levels). In addition, Brain, HP (hypothalamus/pituitary) dysregulation is created and atrophy of the gland as well.
DHEA is also sold over the counter. You can literally go into a health food store and buy a bottle of 25 mg capsules of DHEA. Women should not take DHEA unless absolutely necessary. Women are especially sensitive to DHEA and will not tolerate DHEA if not needed, or if given in too large of an amount. In fact, the majority of men do not need 25 mg DHEA daily. What's the big deal? DHEA can boost estrogen levels or testosterone levels and for women that could mean facial hair, deeper voice, not to mention dys-regulating the steroid hormone family even more. Hormones are very powerful messengers in very tiny amounts. Start playing with the numbers and you could be creating some very serious health problems for yourself. This goes for the men as well. For men, when taking DHEA in higher than needed amounts it will convert to Estrogen.
OK, now that I've gone on and on what are some of the solutions? Medically, I've seen recommendations for prescription drugs such as Effexor, an anti-depressant which has been successful in relieving hot flashes in low doses. The two problems I see here is that #1, it is not solving the problem and #2, there are side-effects to every medication known. You're putting a band-aid on the problem and worse than that you will, in all probability, have a known or unknown side effect from the medication. They are now performing clinical trials on the drug Menerba. From what I can gather it is a plant based drug with 10 or 20 herbs, licorice being the major player. Hmmm, maybe I'll just try some licorice?
Let's look at some of the herbs that may be of value here:
Indicated for hormonal support. Tribulus is known to boost male and female fertility and libido, enhance athletic performance, stamina and endurance, restore and build vitality, relieve menopausal symptoms and is helpful in male menopause.
Black Cohosh -
Is specific for menopausal symptoms such as reproductive problems, especially when accompanied by pain: amenorrhea, dysmenorrhea, uterine pain, ovulatory pain, post-partum pain, testicular and prostatic pain, and menopausal symptomotology such as anxiety, depression and insomnia. It is mildly useful for hot flashes and is more effective when used with Chaste Tree, Motherwort, Licorice, and Dang Gui. Black Cohosh is contraindicated in pregnancy & low blood pressure.
This herb is getting a lot off attention for its' role in decreasing hot flashes. Although a cooling herb Sarsaparilla is more specific for inflammatory conditions of the skin, connective tissue, and bowels. That being said, it does clear blood heat and is used with other herbs to reducef hot flashes.
Red Clover -
The isolated isoflavones are being used to treat menopausal symptoms. Since it is a cooling herb it can help reduce hot flashes.
Licorice - Contains isoflavones and is used for menopausal symptoms such as hot flashes and vaginal dryness. More effective when used with Chastetree, Black Cohosh, Motherwort, and Sage. High doses of Licorice is contraindicated in people with high blood pressure.
Soy - I'm going to be very opinionated here. I don't believe soy is meant for human consumption, there is a tremendous amount of controversy about the efficacy of soy and about the fact that is does not digest in the human body. BTW, soy is not an herb.
Wild Yam - What can I say, some experts swear by it and others say that is has no real benefit for menopausal symptoms, including hot flashes.
When using herbs be sure to purchase your herbs from a known and reputable source. Do a bit of research to be sure the herb is not contraindicated with any medications and/or physical challenges you may have.
No matter how long you have been suffering with hot flashes and/or other symptoms of peri-menopause and menopause, it's not too late to stop hot flashes now. The good news is - You can begin by knowing your triggers and avoiding them. Eat a healthy well balanced diet. Find a qualified herbalist or hormone specialist and discover your hormonal levels so that you can begin the balancing act for a healthier and happier you.