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What Is WilmingtonHormone Replacement Therapy?
HRT (also known as hormone therapy, menopausal hormone therapy, and estrogen replacement therapy) uses female hormones — estrogen and progesterone — to treat common symptoms of menopause and aging. Doctors can prescribe it during or after menopause.
After your period stops, your hormone levels fall, causing uncomfortable symptoms like hot flashes and vaginal dryness, and sometimes conditions like osteoporosis. Wilmington HRT replaces hormones your body no longer makes. It’s the most effective treatment for menopause symptoms.
Side Effects Of Bioidentical Hormones
Testosterone is a major player in the complex mielu of hormones (cellular messengers) that direct our bodies to function. In men who are over the age of 40, there is a significant drop in this level of this hormone. Until recently it was considered taboo to replace this important hormone. But today forward thinking anti-aging specialists realize what scientific studies over the past decade have taught us.
As with women who have gone through the change of life, replacement of their sexual hormones (estrogen, progesterone and testosterone) enact major health benefits such as osteoporosis prevention, heart disease prevention and increases in cognitive function. Likewise for older male subjects the benefits of the addition of testosterone under careful physician management is a crucial aspect of maintaining good health. I wish in this article to dispel some misconceptions about Testosterone Replacement Therapy and provide a list to readers of the benefits of this simple and safe treatment.
First of all there is overwhelming evidence in the scientific literature that testosterone does not cause prostate cancer. In actuality it is the unbalanced estrogen excess in man that is implicated in prostate cancer.
The caveat here is that once there is prostate cancer, testosterone which is an anabolic (building) hormone can promote cancer growth, but contrary to the popular belief, even within the medical field, it does not cause cancer. With advancing age Testosterone levels drop while estrogen levels rise and compete for binding sites on the prostate gland as well as other cells in the body causing a hormonal havoc.
Such problems as an increase in adipose tissue with midsection obesity, a decrease in muscle mass, generalized hormonal imbalances (growth hormone, estrogen, thyroid), depression, increased cholesterol and lipid dysfunction, glucose and insulin imbalance, decreased coronary artery elasticity, elevated blood pressure and loss of a feeling of well being result from low testosterone levels. Supplementing Testosterone in the appropriate candidates reverses these unwanted outcomes, but it is not as simple as taking a pill. There are enzymes in our body that can change exogenous testosterone into other undesirable hormones such as Estrodiol and DHT. Therefore, a physician that understands the balancing act and has the ability to monitor these other hormones is best to treat such a disorder.
Along with the correct replacement modality (cream, gel or patch) there are other considerations which halt the trend of testosterone conversion and these are usually supplemented along with testosterone. Such supplements are Saw palmetto, Zinc and Nettle extract to name a few. In a recent study of the Androderm patch after a 12-month period a depression score dropped by nearly one half with testosterone replacement alone. Again men with complaints of fatigue receiving testosterone in one study had symptoms of fatigue drop for 79% to 10%. A Medline medical literature search reveals many more positive outcomes of testosterone replacement. For those interested in finding out more about their bodies, there is a non-invasive home testing kit available at the Saleeby Longevity Institute which allows men to evaluate the levels of testosterone in circulation.
Andropause the male menopause
by J.P. Saleeby, MD
A point of confusion for some people is the difference between side effects and risks when taking a prescriptive drug. This is certainly true when it comes to hormone replacement therapy or HRT. HRT refers to synthetic hormones prescribed primarily to relieve menopause related complaints such as hot flashes, night sweats, erratic periods, excessive bleeding during perimenopause, etc.
Risks associated with HRT
There are long term risks associated with taking prescriptive hormones as part of replacement therapy. You may have taken prescriptive hormones for years with no side effects whatsoever, and they may have dramatically relieved your menopausal hot flashes, sweats and other complaints. Yet you are now at greater risk for a variety of serious illnesses including breast cancer, uterine cancer, stroke and heart attack to name a few. These are the risks associated with HRT. Research studies have found so many serious risks associated with hormone replacement therapy that most medical doctors are unwilling to routinely prescribe hormone replacement for relief of menopause related complaints. Rightly so, they don't want to put their patient's at risk for life threatening conditions.
Let's look more closely at the risks associated with replacement therapy. Much of our knowledge of these risks comes from the Women's Health Initiative, a study that tracked the health of thousands of women, some taking hrt and others not. The study was eventually stopped as it became clear that there was a dramatically increased risk of breast cancer among the women undergoing HRT. Because of the complex nature of the study, the results are difficult to summarize succinctly. Numerous other studies have also clarified the risks and benefits associated with hormone replacement. Here is a broad picture of the level of risk associated with hormone replacement, followed by the benefits.
Hormone replacement therapy risks
- Breast cancer risk increased by 24 percent with combined estrogen / progestin HRT
- Risk of ischemic stroke increased by 41 percent with medium to high dose HRT, but much less risk with ultra low dose hormone replacement
- Heart attack risk increases by 29 percent for those taking HRT
- Slightly increased risk of ovarian cancer when only estrogen is taken for more than 10 years
- Twenty-one percent increased risk of kidney stones
- Higher risk of developing gall stones
Hormone replacement benefits
- Relief of menopause related complaints
- Increases bone density
- Reduces risk for colon-rectal cancer
- Decreases risk of macular (eye) degeneration and loss of vision associated with aging
The side effects of HRT
Side effects are generally considered to be any temporary complaints that are experienced while taking a drug. Side effects often resolve soon after stopping the medication. Using this description, the side effects of hormone replacement are not well known. These side effects vary depending on which combination of hormones one is taking and the specific synthetic forms used. Some of the more common side effects of prescriptive forms of estrogen, progesterone and combinations of both are as follows.
- Breast pain, enlargement and tenderness is associated with the stimulatory effect of estrogen
- Nausea and vomiting with the use of estrogen HRT taken by mouth
- Vaginal bleeding can occur in association with oral estrogen
- Darkened skin spots tend to occur on the face
- Headaches of a migraine type are associated with taking synthetic progesterone or progestins
- Depression is a common complaint that is found to be a result of taking progestins
- Greasy skin and acne are also associated with progestin use
Women are wisely looking for alternatives to hormone replacement. Fearing the risks associated with it, added to the side effects of prescriptive hormones, they are not too excited by it. Researchers and academics argue for and against hormone replacement.
The author's of a 2008 study titled the Women's International Study of Long-Duration Oestrogen after the Menopausesuggested that their study demonstrated such significant benefits for relief of menopause complaints that HRTshould be reconsidered by many women.
One of their colleagues (not an author of the study) reviewed the results of their study and came up with the opposite conclusion. Underscoring her concerns regarding the risks of hormone replacement therapy, Professor Anne Kavanagh of the University of Melbourne recently countered their claims as to the benefits of hormone replacement therapy. Professor Kavanagh points out that the study did not show and overall improvement in the "quality of life" for women in the study.
Many doctors and patients have been concerned about reports that estrogen replacement raises the risk of cancer, but is not be the case, if done properly.
When progesterone is given along with estrogen for ten or more days per cycle, it not only eliminates the risk of this cancer but may actually reduce it beyond that which occurs spontaneously. Researchers suggest that the progestin was the good guy in combination of estrogen in hormone replacement therapy, first stimulating mitosis, or breast cell division, followed by the reverse, apoptosis. They speculate that a combined continuous regimen of estrogen and progestin could counteract the cell division needed to produce a cancer.
Women on estrogen therapy have a lower risk of dying from breast cancer than those who do not take hormones.
Estrogen alone has been shown to protect against coronary heart disease, lower cholesterol, and preserve brain function. Estrogen replacement not only sharpens memory and lifts the spirit, but it helps protect against Alzheimer's and shows promise as a treatment for the disease. Estrogen and progesterone work in tandem in the body premenopausally and, increasingly, physicians believe that both hormones should be replaced postmenopausally.
Progesterone alone breaks down fat, increases energy through fat loss, protects against endometrial and breast cancer, improves mood and sexual function, and normalizes the levels of blood sugar, zinc, and copper.
The overall beneficial effects of combined estrogen-progesterone replacement make a good case for multihormonal replacement therapy.
By combining these hormones with DHEA and melatonin, both of which have an anti-cancer effect, and growth hormone that stimulates the natural killer cells that fight cancer, you may be able to enjoy all the health-giving, age-reversing benefits of female sex hormone replacement while lowering the risk of cancer. It is important to see a physician regarding this to make sure it is medically monitored and done properly.
Male Hormone Replacement Therapy: Andropause
Bioidentical hormones are often touted as the natural alternative to HRT (Hormone Replacement Therapy) which is the synthetic version of a female's hormones. Bioidentical refers to the progesterone and estrogen that is supposedly identical to the hormones a female's body produces. When a women enters menopause or experiences some other hormonal depletion, many doctors will prescribe hormone replacement therapy as a treatment to the varied symptoms that can accompany hormonal deficiencies.
Because of the dangers associated with HRT, many women have searched for an alternative, which to date, has been bioidentical hormones. This type of hormone compound is usually made in pharmacies that specialize in producing compounds that are regulated for each woman's identical hormone level. Pharmacies that process these compounds are not federal or state regulated so it's never certain as to the quality and consistency of dosages.
The baby boomer generation of women has been the biggest reason for the demand of a more natural way to replace depleting hormones at menopause. Also, this generation is more demanding of natural alternatives to synthetically derived treatments and want a more natural approach that may promise less side effects. The celebrity driven bioidentical conversation has also fueled the demand as many women see famous people who look 20 years younger than their real age.
Some issues to think about when considering the use of natural hormones is the fact that even though bioidenticals are naturally derived, they are still hormones that can affect the body in not only positive but negative ways as well. Also, for women who are impressed with various celebrities who recommend these treatments as a new fountain of youth, remember that celebrities have unlimited access to cosmetic surgeries and other physical assistance to help them achieve the illusion of looking younger.
It is true that natural hormones do not have the synthetic makeup of HRT compounds, but there are still risks as well as benefits associated with their use. Before making your decision about hormonal issues, it is wise to consult with one or more healthcare professionals who can provide a detailed plan for your best health.
Patients interested in bioidentical hormone therapy are encouraged to speak with a medical professional regarding its benefits over traditional hormone replacement therapy techniques. Many clinics offer their patients a consultation in which they will discuss the treatment and will customize a treatment plan for each patient.
In conjunction with this therapy, a medical professional may recommend certain exercise and dietary programs to improve the symptoms of menopause or andropause. It is important that patients work with their physician in creating a specialized therapy program and develop healthy lifestyle practices that will be medically beneficial.
There has been a good deal of confusion and controversy surrounding this treatment in recent years and interested patients are encouraged to discuss the possible risks, benefits and alternatives associated with any treatment or procedure.
Hormone Therapy: What It Is and How It Can Help You
As a woman ages, it is a given fact that she will be hitting her menopause some time in her mid forties. It is also a given that a number of physical and psychological changes accompany this event. Thinning hair, dry skin and wrinkles are some of the effects of menopause. But, what about men? Do they experience something similar?
According to many doctors, many men experience a number of symptoms that are directly associated with their age. As a practicing doctor in Dublin, Ireland put it, men too suffer from a list of problems peculiar to aging. This includes:
* Flailing energy levels
* Depleting sex drive
* Erectile dysfunction
* Increased fat in the midriff area
* Decreased muscle mass
* Falling strength